Systemic mRNA aggregates elicit immunologic reprogramming that unlocks anti-cancer immunity
Successful cancer immunotherapy requires novel approaches that overcome intratumoral immunosuppression and peripheral tolerance. In a recent manuscript describing intravenously administered mRNA-loaded lipid particle aggregates (RNA-LPAs), we demonstrate the ability to reprogram both the tumor micro...
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| Main Authors: | Hector R. Mendez-Gomez, John A. Ligon, Ashley P. Ghiaseddin, Elias J. Sayour |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2025.2543599 |
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