Tumor-secreted RGS17 impairs CD8 + T cell function in lung adenocarcinoma through affecting glucose metabolism mediated by PI3K/AKT pathway
Abstract Background The tumor immune microenvironment (TIME) and its impact on the prognoses and treatment of lung adenocarcinoma (LUAD) represent a major focus of research in this field. The present study primarily elucidates the role of RGS17 in TIME of LUAD. Methods A comprehensive array of analy...
Saved in:
| Main Authors: | Ming Lou, Ji-Chun Tong, Qi-Yong Wu, Zheng Zhu, Xiao-Liang Mao, Jia-Wei Lu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02850-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
BHLHE40-mediated RGS16 upregulation: a driver propelling gastric cancer progression via ferroptosis suppression
by: Caiyun Guo, et al.
Published: (2025-05-01) -
Enhanced glucose metabolism mediated by CD147 is associated with 18F‐FDG PET/CT imaging in lung adenocarcinoma
by: Yufan Zhang, et al.
Published: (2020-05-01) -
Targeting tumor metabolism to augment CD8+ T cell anti-tumor immunity
by: Huan Liu, et al.
Published: (2025-05-01) -
RGS1 stabilized by METTL3-mediated m6A modification promotes the tumorigenicity and macrophage M2 polarization in osteosarcoma
by: Zhizhong Liang, et al.
Published: (2025-10-01) -
Discovering biomarkers associated with infiltration of CD8+ T cells and tumor-associated fibrosis in colon adenocarcinoma using single-cell RNA sequencing and gene co-expression network
by: Jinning Zhang, et al.
Published: (2025-03-01)