Tumor-secreted RGS17 impairs CD8 + T cell function in lung adenocarcinoma through affecting glucose metabolism mediated by PI3K/AKT pathway

Abstract Background The tumor immune microenvironment (TIME) and its impact on the prognoses and treatment of lung adenocarcinoma (LUAD) represent a major focus of research in this field. The present study primarily elucidates the role of RGS17 in TIME of LUAD. Methods A comprehensive array of analy...

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Bibliographic Details
Main Authors: Ming Lou, Ji-Chun Tong, Qi-Yong Wu, Zheng Zhu, Xiao-Liang Mao, Jia-Wei Lu
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02850-3
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