N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1
Abstract Background Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. Although N6-methyladenosine (m6A) methylation is implicated in various pathological processes, its regulatory mechanism in kidne...
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Main Authors: | Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-024-02100-y |
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