N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1

Abstract Background Age-related kidney impairment, characterized by tubular epithelial cell senescence and renal fibrosis, poses a significant global public health threat. Although N6-methyladenosine (m6A) methylation is implicated in various pathological processes, its regulatory mechanism in kidne...

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Bibliographic Details
Main Authors: Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-024-02100-y
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