Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
Abstract The nucleolus is essential for ribosome biogenesis and is involved in many other cellular functions. We performed a systematic spatiotemporal dissection of the human nucleolar proteome using confocal microscopy. In total, 1,318 nucleolar proteins were identified; 287 were localized to fibri...
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| Main Authors: | Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti, Mathias Uhlén, Sara Cuylen‐Haering, Peter J Thul, Emma Lundberg |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020-08-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20209469 |
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