Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder

Abstract The nucleolus is essential for ribosome biogenesis and is involved in many other cellular functions. We performed a systematic spatiotemporal dissection of the human nucleolar proteome using confocal microscopy. In total, 1,318 nucleolar proteins were identified; 287 were localized to fibri...

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Bibliographic Details
Main Authors: Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti, Mathias Uhlén, Sara Cuylen‐Haering, Peter J Thul, Emma Lundberg
Format: Article
Language:English
Published: Springer Nature 2020-08-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20209469
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