Investigating the Causality and Pathogenesis of Primary Sclerosing Cholangitis in Colorectal Cancer Through Mendelian Randomization and Bioinformatics
Conclusion: Our MR study provides evidence that genetic susceptibility to PSC is significantly associated with an increased risk of colorectal cancer in European populations. Analysis of transcriptomic data suggests that NRG1 can be used as a novel biomarker to predict patient prognosis when colorec...
Saved in:
| Main Authors: | Jie Jiao, Honglei Wang, Danping Sun, Wenbin Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Genetics Research |
| Online Access: | http://dx.doi.org/10.1155/genr/5887056 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Bioinformatics analysis reveals shared molecular pathways for relationship between ulcerative colitis and primary sclerosing cholangitis
by: Pooya Jalali, et al.
Published: (2025-05-01) -
IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis
by: Allon Kahn, et al.
Published: (2015-01-01) -
Motion – Patients with Primary Sclerosing Cholangitis Should Undergo Early Liver Transplantation: Arguments against the Motion
by: Jeffrey S Crippin
Published: (2002-01-01) -
Noninvasive diagnostic methods of liver fibrosis in patients with primary biliary cirrhosis and primary sclerosing cholangitis: role of indirect serological markers
by: A. F. Sheptulina, et al.
Published: (2016-08-01) -
Long-term, low-dose immunosuppression for myasthenia does not affect collateral, asymptomatic sclerosing cholangitis
by: Josef Finsterer, et al.
Published: (2012-02-01)