Investigating the Causality and Pathogenesis of Primary Sclerosing Cholangitis in Colorectal Cancer Through Mendelian Randomization and Bioinformatics

Conclusion: Our MR study provides evidence that genetic susceptibility to PSC is significantly associated with an increased risk of colorectal cancer in European populations. Analysis of transcriptomic data suggests that NRG1 can be used as a novel biomarker to predict patient prognosis when colorec...

Full description

Saved in:
Bibliographic Details
Main Authors: Jie Jiao, Honglei Wang, Danping Sun, Wenbin Yu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/genr/5887056
Tags: Add Tag
No Tags, Be the first to tag this record!