Comparative evaluation of DNA and RNA probes for capture-based mitochondrial DNA next-generation sequencing
Abstract Background Probe-based liquid-phase hybridization capture is a powerful and commonly used approach for next-generation sequencing (NGS) of mitochondrial DNA (mtDNA). However, the performance difference between DNA and RNA probe-based capture strategies for mtDNA NGS remains to be determined...
Saved in:
| Main Authors: | Tianlei Sun, Shengjing Li, Yang Liu, Kaixiang Zhou, Jiamin Wang, Zhangwen Lei, Xu Guo, Jinliang Xing, Wenjie Guo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-025-02365-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Analysis of microorganisms and drug-resistance mutations detected by probe-capture metagenomics among HIV-infected patients with pneumonia
by: Qianhui Chen, et al.
Published: (2025-07-01) -
Hybrid Capture-Based Sequencing Enables Highly Sensitive Zoonotic Virus Detection Within the One Health Framework
by: Weiya Mao, et al.
Published: (2025-03-01) -
Detection of gene mutations in genome “hot” spots: “hairpin” amplicons in DNA melting analysis
by: V. N. Kondratova, et al.
Published: (2017-04-01) -
The Effect of Using Probe Thinking Strategy on Legal Acquaintance and Officiating Performance in Volleyball
by: Firas Akram Saleem
Published: (2021-11-01) -
Whole-genome probe capture sequencing reveals genomic diversity and characteristics of Mycoplasma pneumoniae in Nanjing, China
by: Guilan Zhou, et al.
Published: (2025-05-01)