Comparative evaluation of DNA and RNA probes for capture-based mitochondrial DNA next-generation sequencing

Comparative evaluation of DNA and RNA probes for capture-based mitochondrial DNA next-generation sequencing

Abstract Background Probe-based liquid-phase hybridization capture is a powerful and commonly used approach for next-generation sequencing (NGS) of mitochondrial DNA (mtDNA). However, the performance difference between DNA and RNA probe-based capture strategies for mtDNA NGS remains to be determined...

Full description

Saved in:
Bibliographic Details
Main Authors: Tianlei Sun, Shengjing Li, Yang Liu, Kaixiang Zhou, Jiamin Wang, Zhangwen Lei, Xu Guo, Jinliang Xing, Wenjie Guo
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Biology
Subjects:
Mitochondrial DNA
Next-generation sequencing
Probe-based liquid-phase hybridization capture
DNA probes
RNA probes
Online Access:https://doi.org/10.1186/s12915-025-02365-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12915-025-02365-x

Similar Items