PharmaFormer predicts clinical drug responses through transfer learning guided by patient derived organoid
Abstract A major challenge in effective cancer treatment is the variability of drug responses among patients. Patient-derived organoids greatly preserve the genetic and histological characteristics even the drug sensitivities of primary tumor tissues, therefore provide a compelling approach to predi...
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| Main Authors: | Yuru Zhou, Quanhui Dai, Yanming Xu, Shuang Wu, Minzhang Cheng, Bing Zhao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-01082-6 |
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