PharmaFormer predicts clinical drug responses through transfer learning guided by patient derived organoid

Abstract A major challenge in effective cancer treatment is the variability of drug responses among patients. Patient-derived organoids greatly preserve the genetic and histological characteristics even the drug sensitivities of primary tumor tissues, therefore provide a compelling approach to predi...

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Bibliographic Details
Main Authors: Yuru Zhou, Quanhui Dai, Yanming Xu, Shuang Wu, Minzhang Cheng, Bing Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-01082-6
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