Berberine inhibits colorectal liver metastasis via modulation of TGF-β in a cecum transplant mouse model

Abstract Background Hepatic metastasis is the primary cause of colorectal cancer (CRC)-induced death. Our previous results showed the anti-metastatic effects of Coptidis rhizoma using in vitro model. Aim The present study aimed to investigate whether berberine, the main active compound of C. rhizoma...

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Main Authors: Yong-Hwi Kang, Jing-Hua Wang, Jin-Seok Lee, Seung-Ju Hwang, Nam-Hun Lee, Chang-Gue Son
Format: Article
Language:English
Published: BMC 2024-11-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-024-02122-w
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