Nrf2/Nlrp3 signaling in aging BMSCs: Traf6 intervention as a novel approach to osteoporosis treatment

Senile osteoporosis progression is closely related to the decreased osteogenic differentiation capacity of senescent bone marrow stromal stem cells (BMSCs). This study demonstrated that the Traf6-mediated Nrf2/Nlrp3 signaling axis significantly influences inflammatory senescence progression in BMSCs...

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Bibliographic Details
Main Authors: Yajun Li, Yunshang Yang, Donglong Xia, Yiling Fang, Cheng Tang, Jingxian Yu, Dechun Geng, Zhirong Wang, Long Xiao
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725003179
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