Impact of M‐protein detection on the response evaluations of patients undergoing treatment with the IgG‐κ monoclonal antibodies daratumumab or isatuximab, and discrepancies between immunofixation electrophoresis (IFE) systems and reagents

Impact of M‐protein detection on the response evaluations of patients undergoing treatment with the IgG‐κ monoclonal antibodies daratumumab or isatuximab, and discrepancies between immunofixation electrophoresis (IFE) systems and reagents

Abstract Background Immunofixation electrophoresis (IFE) is the standard method for confirming the presence of a monoclonal protein (M‐protein) at multiple myeloma (MM) diagnosis. IFE is also essential at assessment of complete response (CR) and stringent CR during treatment. As the CR assessment is...

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Bibliographic Details
Main Authors: Yuko Shirouchi, Kazumi Kaihara, Tsunaki Sekita, Naoko Amano, Konosuke Nakayama, Kazunori Miyake, Hitoshi Abe, Hirotoshi Oinuma, Dai Maruyama
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Cancer Medicine
Subjects:
cancer management
chemotherapy
hematological cancer
multiple myeloma
Online Access:https://doi.org/10.1002/cam4.70128
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https://doi.org/10.1002/cam4.70128

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