Integrating artificial intelligence and optogenetics for Parkinson’s disease diagnosis and therapeutics in male mice

Integrating artificial intelligence and optogenetics for Parkinson’s disease diagnosis and therapeutics in male mice

Abstract Parkinson’s disease (PD), a progressive neurodegenerative disorder, presents complex motor symptoms and lacks effective disease-modifying treatments. Here we show that integrating artificial intelligence (AI) with optogenetic intervention, termed optoRET, modulating c-RET (REarranged during...

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Main Authors: Bobae Hyeon, Jaehyun Shin, Jae-Hun Lee, Woori Kim, Jea Kwon, Heeyoung Lee, Dae-gun Kim, Choong Yeon Kim, Sian Choi, Jae-Woong Jeong, Kwang-Soo Kim, C. Justin Lee, Daesoo Kim, Won Do Heo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63025-w
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https://doi.org/10.1038/s41467-025-63025-w

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