Homozygous mice with mutant protein FUS[1-359] overexpression: Innovative possibilities for ALS treatment

Homozygous mice with mutant protein FUS[1-359] overexpression: Innovative possibilities for ALS treatment

Introduction: This study investigates a mouse model with overexpression of the mutant FUS[1-359] protein, which can be used to evaluate the effectiveness of gene therapy and other pharmacological interventions for amyotrophic lateral sclerosis (ALS). The model enhances the deeper understanding of th...

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Bibliographic Details
Main Author: Nikita S. Zhunusov
Format: Article
Language:English
Published: Belgorod National Research University 2024-12-01
Series:Research Results in Pharmacology
Subjects:
amyotrophic lateral sclerosis
fused in sarcoma
gene expression
gene therapy
Online Access:https://rrpharmacology.ru/index.php/journal/article/view/554
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