Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients
Mutations in the cardiac ryanodine receptor (RYR2) are the leading cause for catecholaminergic polymorphic ventricular tachycardia (CPVT). In this study, we evaluated antiarrhythmic efficacy of carvedilol and flecainide in CPVT patient-specific induced pluripotent stem cell-derived cardiomyocytes (i...
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Main Authors: | R. P. Pölönen, K. Penttinen, H. Swan, K. Aalto-Setälä |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2018/9109503 |
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