Prediction of drug target interaction based on under sampling strategy and random forest algorithm.

Drug target interactions (DTIs) play a crucial role in drug discovery and development. The prediction of DTIs based on computational method can effectively assist the experimental techniques for DTIs identification, which are time-consuming and expensive. However, the current computational models su...

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Bibliographic Details
Main Authors: Feng Chen, Zhigang Zhao, Zheng Ren, Kun Lu, Yang Yu, Wenyan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318420
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