Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology.

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology.

There is increasing evidence that genetic risk variants for non-syndromic cleft lip/palate (nsCL/P) are also associated with normal-range variation in facial morphology. However, previous analyses are mostly limited to candidate SNPs and findings have not been consistently replicated. Here, we used...

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Main Authors: Laurence J Howe, Myoung Keun Lee, Gemma C Sharp, George Davey Smith, Beate St Pourcain, John R Shaffer, Kerstin U Ludwig, Elisabeth Mangold, Mary L Marazita, Eleanor Feingold, Alexei Zhurov, Evie Stergiakouli, Jonathan Sandy, Stephen Richmond, Seth M Weinberg, Gibran Hemani, Sarah J Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007501&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007501&type=printable

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