SUGAR-DIP trial: oral medication strategy versus insulin for diabetes in pregnancy, study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial

SUGAR-DIP trial: oral medication strategy versus insulin for diabetes in pregnancy, study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial

Introduction In women with gestational diabetes mellitus (GDM) requiring pharmacotherapy, insulin was the established first-line treatment. More recently, oral glucose lowering drugs (OGLDs) have gained popularity as a patient-friendly, less expensive and safe alternative. Monotherapy with metformin...

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Main Authors: Floris Groenendaal, Arie Franx, Rebecca C Painter, Ben Willem Mol, Bas B Van rijn, Leon de Wit, Doortje Rademaker, Daphne N Voormolen, Bettina M C Akerboom, Rosalie M Kiewiet-Kemper, Maarten R Soeters, Marion A L Verwij-Didden, Fahima Assouiki, Daniela H Schippers, Mechteld A R Vermeulen, Simone M I Kuppens, Mirjam M Oosterwerff, Joost J Zwart, Mattheus J M Diekman, Tatjana E Vogelvang, P Rob J Gallas, Sander Galjaard, Willy Visser, Nicole Horree, Tamira K Klooker, Rosemarie Laan, Rik Heijligenberg, Anjoke J M Huisjes, Thomas van Bemmel, Claudia A van Meir, Annewieke W van den Beld, Wietske Hermes, Solrun Vidarsdottir, Anneke G Veldhuis-Vlug, Remke C Dullemond, Henrique J Jansen, Marieke Sueters, Eelco J P de Koning, Judith O E H van Laar, Pleun Wouters-van Poppel, Marina E Sanson-van Praag, Eline S van den Akker, Catherine B Brouwer, Brenda B Hermsen, Bert Jan Potter van Loon, Olivier W H van der Heijden, Bastiaan E de Galan, Marsha van Leeuwen, Johanna A M Wijbenga, Karin de Boer, Arianne C van Bon, Flip W van der Made, Silvia A Eskes, Mirjam Zandstra, William H van Houtum, Babette A M Braams-Lisman, Catharina R G M Daemen-Gubbels, Maurice G A J Wouters, Richard G IJzerman, Nico A Mensing van Charante, Rolf Zwertbroek, Inge M Evers, Harold W de Valk, J Hans deVries
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/8/e029808.full
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