Jiaotai pill and its main component enhance islet hormone secretion in type 2 diabetic rats by activating the THP1/TGase2/SERT/5-HT1FRpathway

Objective: To investigate the relationship between Jiaotai pill (JTP), its main component berberine (BBR), and the serotonin (5-HT) system in regulating islet hormone secretion and alleviating pancreatic β-cell dysfunction during type 2 diabetes mellitus (T2DM) progression. Methods: T2DM rat model w...

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Bibliographic Details
Main Authors: Hongcui Han, Xiaobin Huang, Yanyi Li, Peng Wang, Qing Miao, Yujie Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Traditional Chinese Medical Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095754825000560
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