Integrative network analysis reveals molecular mechanisms of blood pressure regulation

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

Abstract Genome‐wide association studies (GWAS) have identified numerous loci associated with blood pressure (BP). The molecular mechanisms underlying BP regulation, however, remain unclear. We investigated BP‐associated molecular mechanisms by integrating BP GWAS with whole blood mRNA expression pr...

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Main Authors: Tianxiao Huan, Qingying Meng, Mohamed A Saleh, Allison E Norlander, Roby Joehanes, Jun Zhu, Brian H Chen, Bin Zhang, Andrew D Johnson, Saixia Ying, Paul Courchesne, Nalini Raghavachari, Richard Wang, Poching Liu, The International Consortium for Blood Pressure GWAS (ICBP), Christopher J O'Donnell, Ramachandran Vasan, Peter J Munson, Meena S Madhur, David G Harrison, Xia Yang, Daniel Levy
Format: Article
Language:English
Published: Springer Nature 2015-04-01
Series:Molecular Systems Biology
Subjects:
blood pressure
coexpression network
gene expression
hypertension
systems biology
Online Access:https://doi.org/10.15252/msb.20145399
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https://doi.org/10.15252/msb.20145399

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