Studies on chlorophenyl, thiophenyl, and biphenyl clubbed tetrahydro bipyrazole carbaldehydes: Synthesis, antimicrobial and antioxidant activity, SAR study, in-silico pharmacokinetics, toxicity, and molecular modeling

A library of chlorophenyl, thiophenyl, and biphenyl clubbed 3′,4,4′,5-tetrahydro-2′H-[1,3′-bipyrazole]-2′-carbaldehydes was produced via aldolic condensation followed by hetero-cyclization. Synthesized moieties were characterized by IR, 1H, and 13CNMR spectral analysis. The molecular docking was con...

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Bibliographic Details
Main Authors: Avika, Nitin Kumar, Haya Yasin, Shikha Sharma, Suraj N. Mali, Shailesh S. Gurav
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Chemical Physics Impact
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667022424002573
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