Application of Nano-drug Delivery Technology in Overcoming Drug Resistance in Lung Cancer
Lung cancer is one of the most malignant tumor, representing a significant threat to human health. In China, its mortality rate is the highest among all malignant tumors. The occurrence of drug resistance has resulted in unfavourable prognosis for patients with lung cancer, and overcoming drug resis...
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2024-11-01
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| Series: | Chinese Journal of Lung Cancer |
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| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2024.101.30 |
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| author | Yingchun LU Chunyu WANG Bin LIU |
| author_facet | Yingchun LU Chunyu WANG Bin LIU |
| author_sort | Yingchun LU |
| collection | DOAJ |
| description | Lung cancer is one of the most malignant tumor, representing a significant threat to human health. In China, its mortality rate is the highest among all malignant tumors. The occurrence of drug resistance has resulted in unfavourable prognosis for patients with lung cancer, and overcoming drug resistance is a significant challenge that needs to be addressed. Nano-drug delivery technology has been an important approach to overcome drug resistance in lung cancer. Targeting to the mechanisms of drug resistance, by enabling the combined delivery of drugs, increasing the efficiency of drug delivery and improving the targeting and safety of drugs, nano-drug delivery technology offers a novel approach to tackling drug resistance in lung cancer. This paper describes the current status of lung cancer treatment, mechanisms of drug resistance, strategies to overcome drug resistance, and the application of nanotechnology in the diagnosis and treatment of lung cancer. In addition, it summarizes the recent research progress on the application of nano-drug delivery technology to overcome drug resistance in lung cancer. Finally, the current prospects and challenges of nano-drug delivery technology are discussed. |
| format | Article |
| id | doaj-art-fc3f82b7e0dc4c7d8b6836f252ff19e8 |
| institution | Kabale University |
| issn | 1009-3419 1999-6187 |
| language | zho |
| publishDate | 2024-11-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj-art-fc3f82b7e0dc4c7d8b6836f252ff19e82025-01-13T02:46:02ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872024-11-01271186487210.3779/j.issn.1009-3419.2024.101.30Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung CancerYingchun LU0Chunyu WANG1Bin LIU2School of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, ChinaSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 610032, ChinaDepartment of Medical Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital
of University of Electronic Science and Technology of China, Chengdu 610042, ChinaLung cancer is one of the most malignant tumor, representing a significant threat to human health. In China, its mortality rate is the highest among all malignant tumors. The occurrence of drug resistance has resulted in unfavourable prognosis for patients with lung cancer, and overcoming drug resistance is a significant challenge that needs to be addressed. Nano-drug delivery technology has been an important approach to overcome drug resistance in lung cancer. Targeting to the mechanisms of drug resistance, by enabling the combined delivery of drugs, increasing the efficiency of drug delivery and improving the targeting and safety of drugs, nano-drug delivery technology offers a novel approach to tackling drug resistance in lung cancer. This paper describes the current status of lung cancer treatment, mechanisms of drug resistance, strategies to overcome drug resistance, and the application of nanotechnology in the diagnosis and treatment of lung cancer. In addition, it summarizes the recent research progress on the application of nano-drug delivery technology to overcome drug resistance in lung cancer. Finally, the current prospects and challenges of nano-drug delivery technology are discussed.http://dx.doi.org/10.3779/j.issn.1009-3419.2024.101.30lung neoplasmsnano-drug delivery technologydrug resistance |
| spellingShingle | Yingchun LU Chunyu WANG Bin LIU Application of Nano-drug Delivery Technology in Overcoming Drug Resistance in Lung Cancer Chinese Journal of Lung Cancer lung neoplasms nano-drug delivery technology drug resistance |
| title | Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer |
| title_full | Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer |
| title_fullStr | Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer |
| title_full_unstemmed | Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer |
| title_short | Application of Nano-drug Delivery Technology in Overcoming Drug Resistance
in Lung Cancer |
| title_sort | application of nano drug delivery technology in overcoming drug resistance
in lung cancer |
| topic | lung neoplasms nano-drug delivery technology drug resistance |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2024.101.30 |
| work_keys_str_mv | AT yingchunlu applicationofnanodrugdeliverytechnologyinovercomingdrugresistanceinlungcancer AT chunyuwang applicationofnanodrugdeliverytechnologyinovercomingdrugresistanceinlungcancer AT binliu applicationofnanodrugdeliverytechnologyinovercomingdrugresistanceinlungcancer |