Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer

Background Tumor-associated macrophages (TAM) constitute the most abundant immune cells in the tumor stroma initiating pro-inflammatory (M1) or immunosuppressive (M2) responses depending on their polarization status. Advances in tumor immunotherapy call for a detailed understanding of potential immu...

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Bibliographic Details
Main Authors: Victoria Stary, Brigitte Wolf, Daniela Unterleuthner, Julia List, Merjem Talic, Andrea Beer, Johanna Strobl, Georg Stary
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000667.full
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