Convenient Synthesis of 1,4-Dideoxy-1,4-imino-D-ribitol from D-Ribose

Convenient Synthesis of 1,4-Dideoxy-1,4-imino-D-ribitol from D-Ribose

This paper describes a convenient synthesis of 1,4-dideoxy-1,4-imino-D-ribitol (DRB) from D-ribose. L-Lyxonolactone, a key intermediate in this synthesis, was prepared by base-promoted hydrolysis of a 5-chlorinated D-ribonolactone derivative with inversion of configuration at the C-4 position. Cycli...

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Bibliographic Details
Main Authors:	Makoto Oba, Shoi Kawaji, Hironobu Kushima, Takanori Sano, Kozaburo Nishiyama
Format:	Article
Language:	English
Published:	Wiley 2013-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2013/519415
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