Lack of TYK2 signaling enhances host resistance to Candida albicans skin infection

Abstract Candida albicans is the most common human fungal pathogen, causing diseases ranging from local to life-threating systemic infections. Tyrosine kinase 2 (TYK2), a crucial mediator in several cytokine signaling pathways, has been associated with protective functions in various microbial infec...

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Bibliographic Details
Main Authors: Sara Miranda, Caroline Lassnig, Kristina Schmidhofer, Hrönn Kjartansdottir, Claus Vogl, Simone Tangermann, Irina Tsymala, Verena Babl, Mathias Müller, Karl Kuchler, Birgit Strobl
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54888-6
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