A novel multiplexed immunoassay for surface‐exposed proteins in plasma extracellular vesicles

A novel multiplexed immunoassay for surface‐exposed proteins in plasma extracellular vesicles

Abstract Small membranous extracellular vesicles (EV) incorporate proteins and nucleic acids from the parent cell. Proteins exposed on EV surface are dictated by cellular origin and biogenesis pathway. To better understand the EV origin and function, it is important to develop methods that reveal su...

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Bibliographic Details
Main Authors: Emma Tordoff, Jillian Allen, Katya Elgart, Ahmed Elsherbini, Vrinda Kalia, Haotian Wu, Erden Eren, Dimitrios Kapogiannis, Olesia Gololobova, Kenneth Witwer, Olga Volpert, Erez Eitan
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Extracellular Vesicles
Subjects:
assay validation
extracellular vesicles
surface marker analysis
tetraspanin composition
Online Access:https://doi.org/10.1002/jev2.70007
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https://doi.org/10.1002/jev2.70007

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