Multiplex detection of ten ESR1 mutations and AKT1 E17K in breast cancer using digital PCR

Multiplex detection of ten ESR1 mutations and AKT1 E17K in breast cancer using digital PCR

Introduction: ESR1 mutations are now established as a key mechanism of resistance to endocrine therapy in estrogen-receptor–positive breast cancer (ER+ breast cancer) and their sensitive and specific detection in plasma-cell free DNA (plasma-cfDNA) is crucial to monitor during patient treatment. I...

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Bibliographic Details
Main Authors:	Stavroula Smilkou, Aliki Ntzifa, Dimitra Stergiopoulou, Vasilis Georgoulias, Evi Lianidou
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Series:	The Journal of Liquid Biopsy
Subjects:	Estrogen receptor Breast cancer ESR1 mutations Crystal digital PCR Liquid biopsy Plasma-cfDNA
Online Access:	http://www.sciencedirect.com/science/article/pii/S2950195424000195
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