Multiplex detection of ten ESR1 mutations and AKT1 E17K in breast cancer using digital PCR
Introduction: ESR1 mutations are now established as a key mechanism of resistance to endocrine therapy in estrogen-receptor–positive breast cancer (ER+ breast cancer) and their sensitive and specific detection in plasma-cell free DNA (plasma-cfDNA) is crucial to monitor during patient treatment. I...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-09-01
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Series: | The Journal of Liquid Biopsy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2950195424000195 |
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