Phenome-wide investigation of bidirectional causal relationships between major depressive disorder and common human diseases

Abstract The high comorbidity of major depressive disorder (MDD) with other diseases has been well-documented. However, the pairwise causal connections for MDD comorbid networks are poorly characterized. We performed Phenome-wide Mendelian randomization (MR) analyses to explore bidirectional causal...

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Bibliographic Details
Main Authors: Wenxi Sun, Ancha Baranova, Dongming Liu, Hongbao Cao, Xiaobin Zhang, Fuquan Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03216-z
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