Antisera-Neutralizing Capacity of a Highly Evolved Type 2 Vaccine-Derived Poliovirus from an Immunodeficient Patient

Antisera-Neutralizing Capacity of a Highly Evolved Type 2 Vaccine-Derived Poliovirus from an Immunodeficient Patient

Background: The serotype 2 oral poliovirus vaccine (OPV2) can revert to regain wild-type neurovirulence and spread, causing the emergence of vaccine-derived poliovirus (VDPV2) and immunodeficiency-related vaccine-derived polioviruses (iVDPVs). In the United States, testing carried out by the CDC of...

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Bibliographic Details
Main Authors: Yanan Wu, Runfang Zhang, Guangbo Yuan, Lingyu He, Xiaohu Dai, Hongyun Chuan, Mingqing Wang, Jing Liu, Lilan Xu, Guoyang Liao, Weidong Li, Jian Zhou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
poliovirus
type II
pseudovirus
neutralizing antibodies
immunogenicity
Online Access:https://www.mdpi.com/1999-4915/16/11/1761
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