Quantitative measurement of allele‐specific protein expression in a diploid yeast hybrid by LC‐MS

Quantitative measurement of allele‐specific protein expression in a diploid yeast hybrid by LC‐MS

Abstract Understanding the genetic basis of gene regulatory variation is a key goal of evolutionary and medical genetics. Regulatory variation can act in an allele‐specific manner (cis‐acting) or it can affect both alleles of a gene (trans‐acting). Differential allele‐specific expression (ASE), in w...

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Bibliographic Details
Main Authors: Zia Khan, Joshua S Bloom, Sasan Amini, Mona Singh, David H Perlman, Amy A Caudy, Leonid Kruglyak
Format: Article
Language:English
Published: Springer Nature 2012-08-01
Series:Molecular Systems Biology
Subjects:
allele specific
divergence
mass spectrometry
protein expression
proteomics
Online Access:https://doi.org/10.1038/msb.2012.34
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https://doi.org/10.1038/msb.2012.34

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