Fundus Autofluorescence and Clinical Applications
Abstract Fundus autofluorescence (FAF) has allowed in vivo mapping of retinal metabolic derangements and structural changes not possible with conventional color imaging. Incident light is absorbed by molecules in the fundus, which are excited and in turn emit photons of specific wavelengths that are...
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| Format: | Article |
| Language: | English |
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Knowledge E
2021-07-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | https://doi.org/10.18502/jovr.v16i3.9439 |
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| author | Cameron Pole Hossein Ameri |
| author_facet | Cameron Pole Hossein Ameri |
| author_sort | Cameron Pole |
| collection | DOAJ |
| description | Abstract Fundus autofluorescence (FAF) has allowed in vivo mapping of retinal metabolic derangements and structural changes not possible with conventional color imaging. Incident light is absorbed by molecules in the fundus, which are excited and in turn emit photons of specific wavelengths that are captured and processed by a sensor to create a metabolic map of the fundus. Studies on the growing number of FAF platforms has shown each may be suited to certain clinical scenarios. Scanning laser ophthalmoscopes, fundus cameras, and modifications of these each have benefits and drawbacks that must be considered before and after imaging to properly interpret the images. Emerging clinical evidence has demonstrated the usefulness of FAF in diagnosis and management of an increasing number of chorioretinal conditions, such as age-related macular degeneration, central serous chorioretinopathy, retinal drug toxicities, and inherited retinal degenerations such as retinitis pigmentosa and Stargardt disease. This article reviews commercial imaging platforms, imaging techniques, and clinical applications of FAF. |
| format | Article |
| id | doaj-art-faeec64d48b1418999595fa680a2f910 |
| institution | Kabale University |
| issn | 2008-2010 2008-322X |
| language | English |
| publishDate | 2021-07-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj-art-faeec64d48b1418999595fa680a2f9102025-01-13T10:02:33ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2021-07-0116343246110.18502/jovr.v16i3.9439jovr.v16i3.9439Fundus Autofluorescence and Clinical ApplicationsCameron Pole0Hossein Ameri1 Retina Division, USC Roski Eye Institute, Keck School of Medicine, University of South California, Los Angeles, CA, USA Retina Division, USC Roski Eye Institute, Keck School of Medicine, University of South California, Los Angeles, CA, USAAbstract Fundus autofluorescence (FAF) has allowed in vivo mapping of retinal metabolic derangements and structural changes not possible with conventional color imaging. Incident light is absorbed by molecules in the fundus, which are excited and in turn emit photons of specific wavelengths that are captured and processed by a sensor to create a metabolic map of the fundus. Studies on the growing number of FAF platforms has shown each may be suited to certain clinical scenarios. Scanning laser ophthalmoscopes, fundus cameras, and modifications of these each have benefits and drawbacks that must be considered before and after imaging to properly interpret the images. Emerging clinical evidence has demonstrated the usefulness of FAF in diagnosis and management of an increasing number of chorioretinal conditions, such as age-related macular degeneration, central serous chorioretinopathy, retinal drug toxicities, and inherited retinal degenerations such as retinitis pigmentosa and Stargardt disease. This article reviews commercial imaging platforms, imaging techniques, and clinical applications of FAF.https://doi.org/10.18502/jovr.v16i3.9439fundus autofluorescencefundus cameranear-infrared autofluorescenceretinitis pigmentosascanning laser ophthalmoscopeshort-wave autofluorescence |
| spellingShingle | Cameron Pole Hossein Ameri Fundus Autofluorescence and Clinical Applications Journal of Ophthalmic & Vision Research fundus autofluorescence fundus camera near-infrared autofluorescence retinitis pigmentosa scanning laser ophthalmoscope short-wave autofluorescence |
| title | Fundus Autofluorescence and Clinical Applications |
| title_full | Fundus Autofluorescence and Clinical Applications |
| title_fullStr | Fundus Autofluorescence and Clinical Applications |
| title_full_unstemmed | Fundus Autofluorescence and Clinical Applications |
| title_short | Fundus Autofluorescence and Clinical Applications |
| title_sort | fundus autofluorescence and clinical applications |
| topic | fundus autofluorescence fundus camera near-infrared autofluorescence retinitis pigmentosa scanning laser ophthalmoscope short-wave autofluorescence |
| url | https://doi.org/10.18502/jovr.v16i3.9439 |
| work_keys_str_mv | AT cameronpole fundusautofluorescenceandclinicalapplications AT hosseinameri fundusautofluorescenceandclinicalapplications |