Single-cell RNA sequencing and traditional RNA sequencing reveals the role of cancer-associated fibroblasts in head and neck squamous cell carcinomas cohort

Single-cell RNA sequencing and traditional RNA sequencing reveals the role of cancer-associated fibroblasts in head and neck squamous cell carcinomas cohort

Abstract Background Head and neck squamous cell carcinomas (HNSCs) are among the most common tumors worldwide. Despite the availability of various diagnostic and therapeutic strategies, the incidence and mortality rates of HNSC remain high. Cancer-associated fibroblasts (CAFs), as a major component...

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Bibliographic Details
Main Authors: Ling Zhong, Yixin Qiao, Shasha He, Yangju Fu, Jian Zou
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Head and neck squamous cell carcinoma
Cancer-associated fibroblast
Immune cell infiltration
Single-cell RNA sequencing
Online Access:https://doi.org/10.1007/s12672-025-02507-1
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https://doi.org/10.1007/s12672-025-02507-1

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