Rethinking antisense oligonucleotide therapeutics for amyotrophic lateral sclerosis

Abstract Antisense oligonucleotides, which are used to silence target genes, are gaining attention as a novel drug discovery modality for proteinopathies. However, while clinical trials for neurodegenerative diseases like amyotrophic lateral sclerosis have been conducted in recent years, the results...

Full description

Saved in:
Bibliographic Details
Main Authors: Daisuke Ito, Kensuke Okada
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52234
Tags: Add Tag
No Tags, Be the first to tag this record!