The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications

The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications

Preterm birth (PTB), defined as delivery before 37 weeks of gestation, poses a significant global health challenge. This review comprehensively examines the multifaceted role of amnion epithelial cells (AECs) in normal labor induction and preterm birth. AECs, derived from the amniotic ectoderm, exhi...

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Bibliographic Details
Main Authors: Lulu Meng, Jing Yang, Yijie Gao, Yiran Xie, Miaomiao Chen, Wangping Hao, Yi Luo, Ping Ru, Ling Wang, Zhiying He, Ming Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
amniotic epithelial cells (AECs)
preterm birth (PTB)
preterm premature rupture of membranes (PPROM)
cellular senescence (CS)
inflammatory responses
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1590212/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1590212/full

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