Autophagy Regulator Rufy 4 Promotes Osteoclastic Bone Resorption by Orchestrating Cytoskeletal Organization via Its RUN Domain

Autophagy Regulator Rufy 4 Promotes Osteoclastic Bone Resorption by Orchestrating Cytoskeletal Organization via Its RUN Domain

Rufy4, a protein belonging to the RUN and FYVE domain-containing protein family, participates in various cellular processes such as autophagy and intracellular trafficking. However, its role in osteoclast-mediated bone resorption remains uncertain. In this study, we investigated the expression and r...

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Bibliographic Details
Main Authors: Eiko Sakai, Minoru Saito, Yu Koyanagi, Yoshitsugu Takayama, Fatima Farhana, Yu Yamaguchi, Takayuki Tsukuba
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
Rufy4
RUN and FYVE domain-containing protein family
autophagy
osteoclast
bone resorption
cytoskeleton organization
Online Access:https://www.mdpi.com/2073-4409/13/21/1766
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https://www.mdpi.com/2073-4409/13/21/1766

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