The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis

The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis

Over the last few decades, the number of cases of non‐melanoma skin cancer (NMSC) has risen to over 3 million cases every year worldwide. Members of the ERBB receptor family are important regulators of skin development and homeostasis and, when dysregulated, contribute to skin pathogenesis. In this...

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Main Authors: Christine Hoesl, Thomas Fröhlich, Jennifer E. Hundt, Hermann Kneitz, Matthias Goebeler, Ronald Wolf, Marlon R. Schneider, Maik Dahlhoff
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Molecular Oncology
Subjects:
EGFR
ERBB receptors
LRIG2
mouse model
skin carcinogenesis
squamous cell carcinoma
Online Access:https://doi.org/10.1002/1878-0261.12579
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https://doi.org/10.1002/1878-0261.12579

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