Targeting endoplasmic reticulum stress‐induced lymphatic dysfunction for mitigating bisphosphonate‐related osteonecrosis

Targeting endoplasmic reticulum stress‐induced lymphatic dysfunction for mitigating bisphosphonate‐related osteonecrosis

Abstract Background Bisphosphonates (BPs) are the first‐line treatment to stop bone resorption in diseases, including osteoporosis, Paget's disease, multiple myeloma and bone metastases of cancer. However, BPs‐related osteonecrosis of the jaw (BRONJ), characterized by local inflammation and jaw...

Full description

Saved in:
Bibliographic Details
Main Authors: Ziyue Qin, Hanyu Xie, Pengcheng Su, Zesheng Song, Rongyao Xu, Songsong Guo, Yu Fu, Ping Zhang, Hongbing Jiang
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Clinical and Translational Medicine
Subjects:
autophagy
bisphosphonates
endoplasmic reticulum stress
lymphatic drainage
osteonecrosis
Online Access:https://doi.org/10.1002/ctm2.70082
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/ctm2.70082

Similar Items