Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy

Background Immunogenic cell death (ICD) is a peculiar modality of cellular demise that elicits adaptive immune responses and triggers T cell-dependent immunity.Methods Fluorescent biosensors were employed for an unbiased drug screen approach aiming at the identification of ICD enhancers.Results Here...

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Bibliographic Details
Main Authors: Yan Wang, Peng Liu, Wei Xie, Zhen Zhang, Guido Kroemer, Oliver Kepp, Juliette Humeau, Guo Chen, Jonathan Pol
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000462.full
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