Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation

Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation

Introduction. Myeloid-derived suppressor cells (MDSCs) play an important role in restriction of the immune response and are associated with a poor prognosis in cancer. Mobilization of hematopoietic stem cells (HSCs) before high-dose chemotherapy (HCT) with autologous HSC transplantation (auto-HSCT)...

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Bibliographic Details
Main Authors:	T. V. Tyrinova, E. V. Batorov, T. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, A. A. Ostanin, E. R. Chernykh
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2023-01-01
Series:	Сибирский онкологический журнал
Subjects:	multiple myeloma autologous hematopoietic stem cell transplantation time to disease progression myeloid-derived suppressor cells suppressor molecules arginase-1 g-csf
Online Access:	https://www.siboncoj.ru/jour/article/view/2372
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