Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer

Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer

Abstract Background Head and neck cancer (HNC) presents significant research challenges due to the complexity of its tumor microenvironment (TME) and the heterogeneity across different cancer subtypes. Recent advancements in three-dimensional (3D) culture models and organ-on-a-chip (OOC) technology...

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Bibliographic Details
Main Authors: Chen Lin, Zilin Zhang, Feili Yang, Shanshan Gu, Jiyang Zuo, Yi Wu, Jing Zhang, Tiantian Zhou, Yuna Zhang, Zaozao Chen, Zhongze Gu, Zhisen Shen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Head and neck Cancer (HNC)
Tumor microenvironment (TME)
Three-Dimensional models (3D)
Organ-on-a-Chip (OOC)
Personalized medicine
Online Access:https://doi.org/10.1186/s12967-025-06824-5
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https://doi.org/10.1186/s12967-025-06824-5

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