ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts

Abstract Background Although the exact role of mitophagy in the pathogenesis of diabetic cardiomyopathy (DCM) caused by type 2 diabetes mellitus (T2DM) remains controversial, recent studies revealed inhibition of mitophagy exacerbates cardiac injury in DCM. The zinc transporter ZIP7 has been reporte...

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Bibliographic Details
Main Authors: Ningzhi Yang, Rui Zhang, Hualu Zhang, Yonghao Yu, Zhelong Xu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:https://doi.org/10.1186/s12933-024-02499-2
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