Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats

Superoxide anion () is overproduced in joint inflammation, rheumatoid arthritis, and osteoarthritis. Increased production leads to tissue damage, articular degeneration, and pain. In these conditions, the physiological defense against , superoxide dismutases (SOD) are decreased. The complex MnL4 i...

Full description

Saved in:

Bibliographic Details
Main Authors:	Lorenzo Di Cesare Mannelli, Daniele Bani, Andrea Bencini, Maria Luisa Brandi, Laura Calosi, Miriam Cantore, Anna Maria Carossino, Carla Ghelardini, Barbara Valtancoli, Paola Failli
Format:	Article
Language:	English
Published:	Wiley 2013-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2013/905360
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Levels of Malondialdehyde and Superoxide Dismutase in Subclinical Hyperthyroidism
by: Ali Cetinkaya, et al.
Published: (2005-01-01)

Strand-Swapped SH3 Domain Dimer with Superoxide Dismutase Activity
by: Florian R. Häge, et al.
Published: (2025-01-01)

Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum
by: Marcela Capcarova, et al.

Biophysical and spectroscopical insights into structural modulation of species in the aggregation pathway of superoxide dismutase 1
by: Vijay Raj Tomar, et al.
Published: (2025-01-01)

Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst
by: Tiina Kelkka, et al.
Published: (2012-01-01)

Enhancement of superoxide dismutase gene expression in mice following the administration of cinnamon bark extract
by: Ahda Yuni, et al.
Published: (2025-01-01)

Diethyldithiocarbamate Delayed Wound-Induced Callus Formation in Potato Tubers by Inhibiting Superoxide Dismutase
by: CHENG Xinyan, SONG Bingfang, LIU Ning, TIAN Wenmao, YIN Yan, LI Yongcai, BI Yang, WANG Yi
Published: (2024-12-01)

Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study
by: Yinan Hu, et al.
Published: (2025-01-01)

The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells
by: Faranak Korfi, et al.
Published: (2021-01-01)

In Vitro Effect of Sodium Fluoride on Malondialdehyde Concentration and on Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Human Erythrocytes
by: José Gutiérrez-Salinas, et al.
Published: (2013-01-01)

Superoxide dismutase promotes gastric tumorigenesis mediated by Helicobacter pylori and enhances resistance to 5-fluorouracil in gastric cancer
by: Hongbing Fu, et al.
Published: (2025-02-01)

Impact of artificial rice from Gracilaria sp. seaweed on Superoxide Dismutase (SOD) levels in prediabetic and diabetic patients
by: Purwaningsih Sri, et al.
Published: (2024-01-01)

Effects of Antioxidant Therapy on Leukocyte Myeloperoxidase and Cu/Zn-Superoxide Dismutase and Plasma Malondialdehyde Levels in Experimental Colitis
by: Ergul Belge Kurutas, et al.
Published: (2005-01-01)

The relationship between vitamin E and C intake with total activity of erythrocytes and breast milk superoxide dismutase in lactating mothers
by: Ninik Mudjihartini, et al.
Published: (2021-12-01)

The expression of lumican, tight junction protein 1, connective tissue growth factor, superoxide dismutase 1 in corneal tissues in graft disease
by: G.R. Semak, et al.
Published: (2022-07-01)

The effect of docosahexaenoic acid (DHA) supplementation on total antioxidant capacity (TAC), superoxide dismutase (SOD), and interleukin-6 levels in underweight pregnant women
by: Salmon Charles Siahaan, et al.
Published: (2024-11-01)

Protective effects of resveratrol on the expression of catalase, glutathione peroxidase, and superoxide dismutase genes in the ovary and their activity in the serum of rats exposed to lead acetate: An experimental study
by: Mohammad Karimian, et al.
Published: (2025-01-01)

A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report
by: Lucia Grumetto, et al.
Published: (2016-01-01)

Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2
by: Ahn G, et al.
Published: (2025-01-01)

Cognitive Mimetics for Designing Intelligent Technologies
by: Tuomo Kujala, et al.
Published: (2018-01-01)

Genome-Wide Identification of Superoxide Dismutase (<i>SOD</i>) Gene Family in <i>Cymbidium</i> Species and Functional Analysis of <i>CsSOD</i>s Under Salt Stress in <i>Cymbidium sinense</i>
by: Ruyi Li, et al.
Published: (2025-01-01)

A Megamorphic and Two Curious Mimetic Flies
by: Frank M. Hull
Published: (1937-01-01)

Synthesis and Characterization of Glycosaminoglycan Mimetic Variants to Promote Chondrogenesis
by: Richard Vincent, et al.
Published: (2025-01-01)

Revisiting 310-helices: biological relevance, mimetics and applications
by: Diego Núñez-Villanueva
Published: (2024-02-01)

Trichromacy is insufficient for mate detection in a mimetic butterfly
by: Andrew Dang, et al.
Published: (2025-02-01)

Structure‐based computational design of antibody mimetics: challenges and perspectives
by: Elton J. F. Chaves, et al.
Published: (2025-02-01)

Spectral Differentiation and Mimetic Methods for Solving the Scalar Burger’s Equation
by: Bertha K. Rodriguez-Chavez, et al.
Published: (2024-12-01)

Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+
by: Zhian Chen, et al.
Published: (2025-01-01)

Mimetic Gravity: A Review of Recent Developments and Applications to Cosmology and Astrophysics
by: Lorenzo Sebastiani, et al.
Published: (2017-01-01)

Unveiling the link between NADPH oxidase 2 activation and mitochondrial superoxide formation in leukemic cell killing induced by arsenic trioxide
by: Andrea Spina, et al.
Published: (2025-01-01)

Identification of Renox, a Novel Superoxide Producing Enzyme in Kidney
by: Miklós Geiszt, et al.
Published: (2001-01-01)

Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism
by: L. Di Cesare Mannelli, et al.
Published: (2013-01-01)

Arthroscopic Excision of Intra-Articular Hip Osteoid Osteoma: A Report of 2 Cases
by: Alexandre H. Nehme, et al.
Published: (2012-01-01)

Bio-mimetic strategies to re-activate apoptotic cell death for cancer treatments
by: Andrea Venerando, et al.
Published: (2024-11-01)

Design, Fabrication, and Swimming Performance of a Free-Swimming Tuna-Mimetic Robot
by: Sayyed Farideddin Masoomi, et al.
Published: (2014-01-01)

Studies on Production and Chemical Property of Singlet Oxygen and Superoxide Radical by Dyestuffs
by: Vikesh Kumar, et al.
Published: (2009-01-01)

Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
by: Ziyatdinova G.K., et al.
Published: (2015-06-01)

Intra-Articular Dislocation of the Patella
by: Gavin McHugh, et al.
Published: (2013-01-01)

One-step mass-production of CeO2 nanoparticles embedded in free-standing porous carbon as haloperoxidase mimetic coating to combat biofouling on steel surface
by: Chao Zhao, et al.
Published: (2025-01-01)

Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea
by: G. Sadeghi-Hashjin, et al.
Published: (1998-01-01)