Deficiency of calretinin in prefrontal cortex causes behavioral deficits relevant to autism spectrum disorder in mice

Deficiency of calretinin in prefrontal cortex causes behavioral deficits relevant to autism spectrum disorder in mice

Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms including deficits in social interaction, repetitive and stereotyped behaviors, along with higher levels of anxiety and cognitive impairments. Previous studies demonstrate pronounced reduced densi...

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Bibliographic Details
Main Authors: Yaodong Zhang, Xiaotong Zhao, Chao Gao, Shengli Shi, Mengyuan Chen, Bin Guo, Shunan Hu, Daoqi Mei, Xujun Duan, Xiaona Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Brain
Subjects:
Autism spectrum disorder
Calretinin
Action potential
Prefrontal cortex
Mouse model
Online Access:https://doi.org/10.1186/s13041-025-01233-7
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https://doi.org/10.1186/s13041-025-01233-7

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