Human lung organoids reveal conserved CYP1A1 and metallothionein activation in response to particulate matter exposure

Particulate matter (PM) poses significant adverse impacts on respiratory health, yet most studies investigating PM effects have relied on cancer-derived cell lines or animal models with limited physiological relevance to human lung tissue. To address this limitation, we developed functional lung org...

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Bibliographic Details
Main Authors: Seri Choi, Seung-Yeon Kim, Ji Won Baek, Won Keun Oh, Kee K. Kim, Eun-Mi Kim
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325012540
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