Gper1 inhibition exacerbates traumatic brain injury-induced neurological impairments in mice

Abstract Background G protein-coupled estrogen receptor 1 (Gper1) is widely expressed in the brain, while its function in traumatic brain injury (TBI) remains poorly understood. This study aims to investigate the role of Gper1 in TBI pathology and the underlying mechanisms using a mouse model. Metho...

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Bibliographic Details
Main Authors: Ya-Fei Xue, Ying-Xi Wu, Yun-Ze Zhang, Tian-Zhi Zhao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Behavioral and Brain Functions
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Online Access:https://doi.org/10.1186/s12993-025-00281-2
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